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Risk of Major Adverse Cardiovascular Events Among Users of Naldemedine Compared With Other Medications Used for Opioid Induced Constipation in Adult Patients With Chronic Non-Cancer Pain in a Healthcare Claims Database

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Trial Profile

Risk of Major Adverse Cardiovascular Events Among Users of Naldemedine Compared With Other Medications Used for Opioid Induced Constipation in Adult Patients With Chronic Non-Cancer Pain in a Healthcare Claims Database

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 19 Feb 2025

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At a glance

  • Drugs Naldemedine (Primary) ; Lubiprostone; Naloxegol
  • Indications Constipation
  • Focus Adverse reactions
  • Sponsors Shionogi

Most Recent Events

  • 28 Feb 2022 Planned End Date changed from 1 Nov 2025 to 1 Nov 2030.
  • 28 Feb 2022 Planned primary completion date changed from 1 Nov 2025 to 1 Nov 2030.
  • 02 Apr 2019 Status changed from not yet recruiting to recruiting.

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