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Investigation of the Activity of Vidofludimus Calcium, a Novel, Orally Available, Small Molecule Inhibitor of Dihydroorotate Dehydrogenase, as a Treatment for Primary Sclerosing Cholangitis (PSC)

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Trial Profile

Investigation of the Activity of Vidofludimus Calcium, a Novel, Orally Available, Small Molecule Inhibitor of Dihydroorotate Dehydrogenase, as a Treatment for Primary Sclerosing Cholangitis (PSC)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 19 Oct 2022

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At a glance

  • Drugs Vidofludimus calcium (Primary)
  • Indications Primary sclerosing cholangitis
  • Focus Proof of concept; Therapeutic Use

    • Most Recent Events

    • 18 Feb 2021 According to an Immunic media release. the company is in discussions with investigators and leading clinical experts to further evaluate the data set and to explore potential next steps for this indication.
    • 18 Feb 2021 According to an Immunic media release, A total of 18 patients started treatment of 30 mg IMU-838. Of these patients received the full 24-week treatment with IMU-838.
    • 18 Feb 2021 According to an Immunic media release, due to the high number of discontinued patients during the COVID-19 pandemic and the fact that all discontinued patients in an ITT statistical analysis will be counted as treatment failures at week 24, this analysis focuses mainly on the 11-patient PP population.
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