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A Phase 3 Randomized, Placebo-controlled, Double-blind Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Subjects With Metastatic Prostate Cancer

Trial Profile

A Phase 3 Randomized, Placebo-controlled, Double-blind Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Subjects With Metastatic Prostate Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 29 May 2025

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At a glance

  • Drugs Abiraterone acetate/niraparib (Primary) ; Abiraterone acetate; Niraparib; Prednisone
  • Indications Prostate cancer
  • Focus Biomarker; Therapeutic Use
  • Acronyms MAGNITUDE
  • Sponsors Janssen Research & Development; Janssen-Cilag

Most Recent Events

  • 02 May 2025 Planned End Date changed from 19 Feb 2027 to 27 Feb 2027.
  • 02 Apr 2025 Planned End Date changed from 19 Mar 2027 to 19 Feb 2027.
  • 20 Feb 2025 Planned End Date changed from 19 Feb 2027 to 19 Mar 2027.

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