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A Multicenter, Randomized, Placebo-Controlled, Double-Blind, Phase 1b Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL747 in Subjects With Amyotrophic Lateral Sclerosis

Trial Profile

A Multicenter, Randomized, Placebo-Controlled, Double-Blind, Phase 1b Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL747 in Subjects With Amyotrophic Lateral Sclerosis

Recruiting
Phase of Trial: Phase I

Latest Information Update: 15 Feb 2019

At a glance

  • Drugs DNL-747 (Primary)
  • Indications Amyotrophic lateral sclerosis
  • Focus Adverse reactions
  • Sponsors Denali Therapeutics Inc
  • Most Recent Events

    • 08 Jan 2019 According to a Denali Therapeutics media release, first patient has been dosed in this study.
    • 08 Jan 2019 According to a Denali Therapeutics media release, data readout from this Phase 1b study is expected during fourth quarter of 2019.
    • 08 Jan 2019 Planned number of patients changed from 16 to 26, according to a Denali Therapeutics media release
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