A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Nirogacestat Versus Placebo in Adult Patients With Progressing Desmoid Tumors/Aggressive Fibromatosis (DT/AF)

Status: Completed

Phase of Trial: Phase III

Latest Information Update: 26 Feb 2025

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At a glance

20 Feb 2025 According to a SpringWorks Therapeutics media release, company presented long-term follow-up data from the Phase 3 DeFi trial of nirogacestat in adults with progressing desmoid tumors at the 2024 Connective Tissue Oncology Society Annual Meeting.
20 Feb 2025 According to a SpringWorks Therapeutics media release, if the EMA approves MAA company expects to launch OGSIVEO following reimbursement authorization in individual EU countries, beginning with Germany in mid-2025
31 Jan 2025 Status changed from active, no longer recruiting to completed.

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