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Cetuximab and Vemurafenib Plus FOLFIRI for BRAF V600E Mutated Advanced Colorectal Cancer (IMPROVEMENT): A Single-arm Study

Trial Profile

Cetuximab and Vemurafenib Plus FOLFIRI for BRAF V600E Mutated Advanced Colorectal Cancer (IMPROVEMENT): A Single-arm Study

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 04 Aug 2023

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At a glance

  • Drugs Cetuximab (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Vemurafenib (Primary)
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Therapeutic Use
  • Acronyms IMPROVEMENT

Most Recent Events

  • 12 Jan 2022 Results (n=21 enrolled between 12th January 2018, and 18th June 2021) published in the European Journal of Cancer
  • 15 Aug 2021 Planned End Date changed from 31 Dec 2020 to 31 Dec 2022.
  • 15 Aug 2021 Planned primary completion date changed from 1 Dec 2020 to 1 Dec 2021.

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