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A Randomized, Double-Blind, Placebo-Controlled, Cross-over Phase 2 Study of Continuous 8-Hour Intravenous Infusions of BMS-986231 in Patients With Heart Failure and Impaired Systolic Function Given a Standard Dose of Loop Diuretic

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Cross-over Phase 2 Study of Continuous 8-Hour Intravenous Infusions of BMS-986231 in Patients With Heart Failure and Impaired Systolic Function Given a Standard Dose of Loop Diuretic

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 27 Nov 2023

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At a glance

  • Drugs Cimlanod (Primary) ; Furosemide (Primary)
  • Indications Heart failure
  • Focus Pharmacodynamics
  • Sponsors Bristol-Myers Squibb

Most Recent Events

  • 12 Nov 2023 Primary endpoint has been met. (4-hour Urinary Output Following Intravenous Administration of 40 mg Furosemide to HFrEF Participants Receiving BMS-986231 Infusion Compared to Placebo), as per Results published in the European Journal of Heart Failure
  • 12 Nov 2023 Results published in the European Journal of Heart Failure
  • 29 Jan 2020 Status changed from active, no longer recruiting to completed.

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