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Efficacy and Safety of LY3298176 Once Weekly Versus Insulin Glargine in Patients With Type 2 Diabetes and Increased Cardiovascular Risk (SURPASS-4)

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Trial Profile

Efficacy and Safety of LY3298176 Once Weekly Versus Insulin Glargine in Patients With Type 2 Diabetes and Increased Cardiovascular Risk (SURPASS-4)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 30 Jan 2024

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At a glance

  • Drugs Tirzepatide (Primary) ; Insulin glargine
  • Indications Type 2 diabetes mellitus
  • Focus Registrational; Therapeutic Use
  • Acronyms SURPASS-4
  • Sponsors Eli Lilly and Company

    • Most Recent Events

    • 25 Jan 2024 Results assessing the evaluate gastrointestinal adverse events (AEs) and the impact of nausea, vomiting or diarrhoea (N/V/D) and any gastrointestinal (GI) AEs overall on weight change with tirzepatide from SURPASS 1-5 Trials, published in the Diabetes, Obesity and Metabolism
    • 13 Nov 2023 Results comparing the effect of TZP and insulin glargine (iGlar) on hsCRP in patients with T2D and established or high risk for cardiovascular (CV) disease, presented at the American Heart Association Scientific Sessions 2023
    • 13 Nov 2023 Results assessing the ASCVD risk in T2D participants without CVD history from SURPASS 1-5 Trials, presented at the American Heart Association Scientific Sessions 2023

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