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A Randomized Phase III Study of Ibrutinib Plus Obinutuzumab Versus Ibrutinib Plus Venetoclax and Obinutuzumab in Untreated Older Patients (>/= 70 Years of Age) With Chronic Lymphocytic Leukemia (CLL)

Trial Profile

A Randomized Phase III Study of Ibrutinib Plus Obinutuzumab Versus Ibrutinib Plus Venetoclax and Obinutuzumab in Untreated Older Patients (>/= 70 Years of Age) With Chronic Lymphocytic Leukemia (CLL)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 11 Dec 2019

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At a glance

  • Drugs Ibrutinib (Primary) ; Obinutuzumab (Primary) ; Venetoclax (Primary)
  • Indications Chronic lymphocytic leukaemia
  • Focus Therapeutic Use
  • Most Recent Events

    • 06 Nov 2019 The study includes two interim analyses for superiority when 50% and 75% of the expected number of events have been observed and three interim analyses for futility when 25%, 50%, and 75% of the expected number of events have been observed, This study is expected to accrue for 3 years beginning January 2019, and we welcome participation from sites throughout the NCTN as per trial design released at the 61st Annual Meeting and Exposition of the American Society of Hematology
    • 06 Nov 2019 Trial design released at the 61st Annual Meeting and Exposition of the American Society of Hematology
    • 11 Jan 2019 Status changed from not yet recruiting to recruiting.
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