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A Phase 1, Open-Label, Multicenter, Dose Escalation Study of mRNA-2752, a Lipid Nanoparticle Encapsulating mRNAs Encoding Human OX40L, IL-23, and IL-36γ, for Intratumoral Injection Alone and in Combination With Immune Checkpoint Blockade

Trial Profile

A Phase 1, Open-Label, Multicenter, Dose Escalation Study of mRNA-2752, a Lipid Nanoparticle Encapsulating mRNAs Encoding Human OX40L, IL-23, and IL-36γ, for Intratumoral Injection Alone and in Combination With Immune Checkpoint Blockade

Recruiting
Phase of Trial: Phase I

Latest Information Update: 11 Feb 2019

At a glance

  • Drugs Durvalumab (Primary) ; MRNA 2752 (Primary) ; Tremelimumab (Primary)
  • Indications Lymphoma; Solid tumours
  • Focus Adverse reactions
  • Sponsors Moderna Therapeutics
  • Most Recent Events

    • 08 Jan 2019 According to a Moderna Therapeutics media release, the cfirst patient has been dosed in the trial.
    • 21 Nov 2018 New trial record
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