Trial Profile

PHOENIX DDR/Anti-PD-L1 Trial: A Pre-surgical Window of Opportunity and Post-surgical Adjuvant Biomarker Study of DNA Damage Response Inhibition and/or Anti-PD-L1 Immunotherapy in Patients With Neoadjuvant Chemotherapy Resistant Residual Triple Negative Breast Cancer

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 02 Aug 2023

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At a glance

Drugs Ceralasertib (Primary) ; Durvalumab (Primary) ; Olaparib (Primary)
Indications Advanced breast cancer; Early breast cancer; Triple negative breast cancer
Focus Biomarker; Pharmacogenomic; Therapeutic Use
Acronyms PHOENIX

15 Apr 2020 Status changed from recruiting to suspended.
19 Feb 2020 Planned End Date changed from 1 Aug 2023 to 1 Dec 2025.
19 Feb 2020 Planned primary completion date changed from 1 May 2021 to 1 Mar 2023.

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