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A Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study to Evaluate the Efficacy, Safety, and Tolerability of Three Doses of NGM282 Administered for 24 Weeks for the Treatment of Histologically Confirmed Nonalcoholic Steatohepatitis (NASH)

Trial Profile

A Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study to Evaluate the Efficacy, Safety, and Tolerability of Three Doses of NGM282 Administered for 24 Weeks for the Treatment of Histologically Confirmed Nonalcoholic Steatohepatitis (NASH)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 25 Nov 2020

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At a glance

  • Drugs Aldafermin (Primary)
  • Indications Non-alcoholic steatohepatitis
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ALPINE 2/3
  • Sponsors NGM Biopharmaceuticals
  • Most Recent Events

    • 19 Nov 2020 Planned End Date changed from 1 Dec 2020 to 1 Sep 2021.
    • 19 Nov 2020 Planned primary completion date changed from 1 Sep 2020 to 1 Jun 2021.
    • 29 Aug 2020 Status changed from recruiting to active, no longer recruiting, according to a NGM Biopharmaceuticals media release.
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