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Multicenter Double Blind Randomized Phase II Trial of Olaparib vs Placebo as Maintenance Therapy in Platinum-sensitive Advanced Endometrial Carcinoma

Trial Profile

Multicenter Double Blind Randomized Phase II Trial of Olaparib vs Placebo as Maintenance Therapy in Platinum-sensitive Advanced Endometrial Carcinoma

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 Dec 2024

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At a glance

  • Drugs Carboplatin (Primary) ; Olaparib (Primary) ; Paclitaxel (Primary)
  • Indications Carcinoma; Endometrial cancer
  • Focus Therapeutic Use
  • Acronyms GINECO-UTOLA; UTOLA
  • Sponsors AstraZeneca

Most Recent Events

  • 04 Dec 2024 Status changed from active, no longer recruiting to completed.
  • 24 Oct 2023 Primary endpoint (Efficacy: Progression free survival (PFS1) according to modified Response Evaluation Criteria in Solid Tumors (RECIST version 1.1) of Olaparib maintenance after a platinum based chemotherapy in patients with advanced or metastatic endometrial cancer) has not been met, according to Results presented at the 48th European Society for Medical Oncology Congress.
  • 06 Sep 2021 Status changed from recruiting to active, no longer recruiting.

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