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Safety, Tolerability, and Pharmacokinetics of Multiple Rising Oral Doses of BI 1358894 (Double-blind, Randomised, Placebo-controlled, Parallel-group Design) and Evaluation of Midazolam Interaction (Nested, Open, Fixed-sequence, Intra-individual Comparison) in Healthy Male Subjects

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Trial Profile

Safety, Tolerability, and Pharmacokinetics of Multiple Rising Oral Doses of BI 1358894 (Double-blind, Randomised, Placebo-controlled, Parallel-group Design) and Evaluation of Midazolam Interaction (Nested, Open, Fixed-sequence, Intra-individual Comparison) in Healthy Male Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs BI 1358894 (Primary) ; Midazolam
  • Indications Major depressive disorder
  • Focus Adverse reactions
  • Sponsors Boehringer Ingelheim

    • Most Recent Events

    • 15 Sep 2020 Results assessing tolerability and drug-related AEs presented at the 33rd Annual Congress of the European College of Neuropsychopharmacology
    • 17 Jul 2019 Status changed from active, no longer recruiting to completed.
    • 25 Jun 2019 Status changed from recruiting to active, no longer recruiting.

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