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A Phase 2b/3, Prospective, Randomized, Double-masked, Active Comparator-controlled, Multi-center Study to Investigate the Efficacy and Safety of Repeated Intravitreal Administration of KSI-301 in Subjects With Neovascular (Wet) Age-related Macular Degeneration

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Trial Profile

A Phase 2b/3, Prospective, Randomized, Double-masked, Active Comparator-controlled, Multi-center Study to Investigate the Efficacy and Safety of Repeated Intravitreal Administration of KSI-301 in Subjects With Neovascular (Wet) Age-related Macular Degeneration

Status: Discontinued
Phase of Trial: Phase II/III

Latest Information Update: 12 Sep 2023

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At a glance

  • Drugs Tarcocimab tedromer (Primary) ; Aflibercept
  • Indications Wet age-related macular degeneration
  • Focus Registrational; Therapeutic Use
  • Acronyms DAZZE wet AMD; DAZZLE
  • Sponsors Kodiak Sciences

    • Most Recent Events

    • 02 Jun 2022 Status changed from active, no longer recruiting to discontinued as primary endpoint not met.
    • 18 May 2022 This trial has been discontinued in Poland according to European Clinical Trials Database record.
    • 29 Apr 2022 According to a Kodiak Sciences media release, data from this trial will be presented at the Association for Research in Vision and Ophthalmology (ARVO) 2022 Annual Meeting and Retina World Congress 2022.
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