Trial Profile

A Phase 1, First-in-Human, Open-Label, Dose Escalation and Cohort Expansion Study of MGD019, a Bispecific DART Protein Binding PD-1 and CTLA-4 in Patients With Unresectable or Metastatic Neoplasms

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 10 Mar 2025

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At a glance

Drugs Lorigerlimab (Primary)
Indications Carcinoma; Colorectal cancer; Fallopian tube cancer; Malignant melanoma; Non-small cell lung cancer; Prostate cancer; Skin cancer; Solid tumours; Squamous cell cancer; Thymoma
Focus Adverse reactions; First in man
Sponsors MacroGenics

Most Recent Events

06 Mar 2025 Status changed from active, no longer recruiting to completed.
13 Sep 2024 Planned End Date changed from 1 Dec 2024 to 1 Jan 2025.
13 Feb 2024 Planned End Date changed from 1 Sep 2024 to 1 Dec 2024.

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