A Multicenter, Open Label, Phase II Basket Trial Exploring the Efficacy and Safety of the Combination of Rucaparib (PARP Inhibitor) and Atezolizumab (Anti-PD-L1 Antibody) in Patients With DNA Repair-deficient or Platinum-sensitive Solid Tumors
Latest Information Update: 28 Mar 2024
At a glance
- Drugs Atezolizumab (Primary) ; Rucaparib (Primary)
- Indications Adenocarcinoma; Bladder cancer; Carcinoma; Gastric cancer; Non-small cell lung cancer; Oesophageal cancer; Prostate cancer; Renal cell carcinoma; Urogenital cancer
- Focus Therapeutic Use
- Acronyms ARIANES
- 25 Mar 2024 Planned primary completion date changed from 1 Apr 2024 to 1 Dec 2024.
- 19 Jan 2023 Status changed from recruiting to suspended.
- 13 Sep 2022 Results of platinum-sensitive metastatic urothelial cancer (mUC) and metastatic castration-resistant prostate cancer cohorts, presented at the 47th European Society for Medical Oncology Congress.