Trial Profile

A Phase III, Multicenter, Randomized, Double-blind Study to Assess Efficacy and Safety of Two Doses of Crizanlizumab Versus Placebo, With or Without Hydroxyurea/ Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients With Vaso-Occlusive Crises (STAND)

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 21 Sep 2026

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At a glance

Drugs Crizanlizumab (Primary)
Indications Vaso-occlusive crisis
Focus Registrational; Therapeutic Use
Acronyms STAND
Sponsors Novartis Healthcare; Novartis Pharma A.G.; Novartis Pharmaceuticals

14 Sep 2026 Planned End Date changed from 23 Nov 2026 to 5 Nov 2026.
27 Jan 2026 Planned End Date changed from 14 Dec 2026 to 23 Nov 2026.
24 Jan 2024 This trial has been Completed in Greece, According to European Clinical Trials Database record.

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