Trial Profile

A Phase III, Multicenter, Randomized, Double-blind Study to Assess Efficacy and Safety of Two Doses of Crizanlizumab Versus Placebo, With or Without Hydroxyurea/ Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients With Vaso-Occlusive Crises (STAND)

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 07 Apr 2025

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At a glance

Drugs Crizanlizumab (Primary)
Indications Vaso-occlusive crisis
Focus Registrational; Therapeutic Use
Acronyms STAND
Sponsors Novartis Healthcare; Novartis Pharma A.G.; Novartis Pharmaceuticals

24 Jan 2024 This trial has been Completed in Greece, According to European Clinical Trials Database record.
12 Dec 2023 Results of pooled analysis from studies (NCT0189536, NCT03264989, NCT03474965 and NCT03814746 )in patients with SCD, presented at 65th Annual Meeting and Exposition of the American Society of Hematology.
12 Dec 2023 Results(n=252) presented at the 65th American Society of Hematology Annual Meeting and Exposition

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