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A Phase III, Multicenter, Randomized, Double-blind Study to Assess Efficacy and Safety of Two Doses of Crizanlizumab Versus Placebo, With or Without Hydroxyurea/ Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients With Vaso-Occlusive Crises (STAND)

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Trial Profile

A Phase III, Multicenter, Randomized, Double-blind Study to Assess Efficacy and Safety of Two Doses of Crizanlizumab Versus Placebo, With or Without Hydroxyurea/ Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients With Vaso-Occlusive Crises (STAND)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 14 Jan 2020

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At a glance

  • Drugs Crizanlizumab (Primary)
  • Indications Vaso-occlusive crisis
  • Focus Therapeutic Use
  • Acronyms STAND
  • Sponsors Novartis; Novartis Pharmaceuticals

    • Most Recent Events

    • 10 Dec 2019 Trial design presented at the 61st Annual Meeting and Exposition of the American Society of Hematology.
    • 30 Sep 2019 Planned End Date changed from 2 Dec 2027 to 5 Nov 2027.
    • 29 Jun 2019 Planned initiation date (Estimated date of first participant enrollement) changed from 29 Apr 2019 to 25 Jul 2019.
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