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A Phase I/Ib Open-Label, Multi-Center, Dose-Escalation Study to Investigate the Safety, Pharmacokinetics and Preliminary Efficacy of Intravenous NBF 006 in Patients With Non-Small Cell Lung, Pancreatic, or Colorectal Cancer Followed by a Dose Expansion Study in Patients With KRAS-Mutated Non-Small Cell Lung Cancer

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A Phase I/Ib Open-Label, Multi-Center, Dose-Escalation Study to Investigate the Safety, Pharmacokinetics and Preliminary Efficacy of Intravenous NBF 006 in Patients With Non-Small Cell Lung, Pancreatic, or Colorectal Cancer Followed by a Dose Expansion Study in Patients With KRAS-Mutated Non-Small Cell Lung Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 29 Jul 2024

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At a glance

  • Drugs NBF 006 (Primary)
  • Indications Colorectal cancer; Non-small cell lung cancer; Pancreatic cancer
  • Focus Adverse reactions; First in man
  • Sponsors Nitto Biopharma

    • Most Recent Events

    • 24 Jul 2024 Status changed from active, no longer recruiting to completed.
    • 30 Aug 2023 Status changed from recruiting to active, no longer recruiting.
    • 06 Jun 2023 Results (n=21) assessing the safety, tolerability, and PK of NBF-006 in patients with non-small cell lung, pancreatic, or colorectal cancer, presented at the 59th Annual Meeting of the American Society of Clinical Oncology.

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