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A Phase 1b/2a Multi-center Study to Assess the Safety, Tolerability, Pharmacokinetics of CTX-009 (ABL001) in Combination With Irinotecan or Paclitaxel in Patients With Advanced or Metastatic Solid Tumors

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Trial Profile

A Phase 1b/2a Multi-center Study to Assess the Safety, Tolerability, Pharmacokinetics of CTX-009 (ABL001) in Combination With Irinotecan or Paclitaxel in Patients With Advanced or Metastatic Solid Tumors

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 29 Jan 2025

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At a glance

  • Drugs CTX 009 (Primary) ; Irinotecan (Primary) ; Paclitaxel (Primary)
  • Indications Biliary cancer; Cholangiocarcinoma; Colorectal cancer; Gallbladder cancer; Gastric cancer; Ovarian cancer; Periampullary cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Handok Inc

    • Most Recent Events

    • 27 Jan 2025 Status changed from active, no longer recruiting to discontinued.
    • 21 Dec 2023 Status changed from recruiting to active, no longer recruiting.
    • 21 Jan 2023 Preliminary results (n=24; from Phase 2 study) assessing safety and efficacy of CTX-009 in combination with paclitaxel or irinotecan in patients with advanced solid tumorspresented at the 2023 Gastrointestinal Cancers Symposium

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