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Pyrotinib, Dalpiciclib(SHR6390) and Endocrine Therapy in Subjects With Dual-receptor Positive(ER+/HER2+) Advanced Breast Cancer: a Multi-center Phase Ib/II Study

Trial Profile

Pyrotinib, Dalpiciclib(SHR6390) and Endocrine Therapy in Subjects With Dual-receptor Positive(ER+/HER2+) Advanced Breast Cancer: a Multi-center Phase Ib/II Study

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 27 Jun 2023

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At a glance

  • Drugs Dalpiciclib (Primary) ; Fulvestrant (Primary) ; Letrozole (Primary) ; Pyrotinib (Primary)
  • Indications Advanced breast cancer; HER2 positive breast cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms PLEASURABLE
  • Most Recent Events

    • 06 Jun 2023 Results (As of January 19, 2023, n=48) presented at the 59th Annual Meeting of the American Society of Clinical Oncology
    • 05 Mar 2023 Planned End Date changed from 12 Dec 2022 to 10 Dec 2025.
    • 05 Mar 2023 Planned primary completion date changed from 12 Jun 2020 to 10 Jun 2023.

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