Trial Profile

An Investigator Sponsored Phase I Study of the Safety, Tolerability and Pharmacodynamics of Escalating Doses of Combination Treatment of AZD5363 + Olaparib + Durvalumab (MEDI4736) in Patients With Advanced or Metastatic Solid Tumor Malignancies

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 06 Aug 2025

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At a glance

22 Jul 2025 Planned End Date changed from 31 Dec 2023 to 31 Dec 2026.
22 Jul 2025 Planned primary completion date changed from 31 Dec 2021 to 31 Dec 2026.
13 Sep 2022 Results (n=39) reporting efficacy data from both dose escalation and expansion cohorts presented at the 47th European Society for Medical Oncology Congress

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