Phase I/II Safety and Efficacy Study of Autophagy Inhibition With Hydroxychloroquine to Augment the Antiproliferative and Biological Effects of Pre-Operative Palbociclib Plus Letrozole for Estrogen Receptor-Positive and HER2-Negative Breast Cancer
Latest Information Update: 20 Feb 2025
At a glance
- Drugs Hydroxychloroquine (Primary) ; Letrozole (Primary) ; Palbociclib (Primary)
- Indications Advanced breast cancer; Early breast cancer; HER2 negative breast cancer
- Focus Adverse reactions; Therapeutic Use
Most Recent Events
- 18 Apr 2024 Status changed from active, no longer recruiting to completed.
- 15 Nov 2023 Planned End Date changed from 31 Dec 2024 to 31 Dec 2025.
- 15 Nov 2023 Planned primary completion date changed from 31 Dec 2023 to 31 Dec 2025.