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A Phase 3b, Randomized, Double-blind, Multicenter Study to Evaluate the Safety and Efficacy of Intravenous Re-induction Therapy With Ustekinumab in Patients With Moderately to Severely Active Crohn's Disease

Trial Profile

A Phase 3b, Randomized, Double-blind, Multicenter Study to Evaluate the Safety and Efficacy of Intravenous Re-induction Therapy With Ustekinumab in Patients With Moderately to Severely Active Crohn's Disease

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 06 Feb 2025

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At a glance

  • Drugs Ustekinumab (Primary) ; Ustekinumab
  • Indications Crohn's disease
  • Focus Registrational; Therapeutic Use
  • Acronyms POWER
  • Sponsors Janssen-Cilag

Most Recent Events

  • 17 Oct 2023 Results presented at the 31st United European Gastroenterology Week
  • 17 Oct 2023 Results of subgroup analysis assessing Clinical Outcomes and Biomarker Normalisation Response at Week 16 in Patients with Inadequate Response or Intolerance to Prior Biologics presented at the 31st United European Gastroenterology Week
  • 17 Oct 2023 Results assessing Pharmacokinetics, Exposure Response Relationships, and Immunogenicity in Crohns Disease Patients with Ustekinumab Secondary Loss of Response Following Ustekinumab IV Re Induction from the Week 16 presented at the 31st United European Gastroenterology Week

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