A Phase II Study Assessing the Efficacy of Osimertinib in Combination With Savolitinib in Patients With EGFRm+ and MET+, Locally Advanced or Metastatic Non Small Cell Lung Cancer Who Have Progressed Following Treatment With Osimertinib
Latest Information Update: 13 Feb 2026
At a glance
- Drugs Osimertinib (Primary) ; Savolitinib (Primary)
- Indications Non-small cell lung cancer
- Focus Therapeutic Use
- Acronyms SAVANNAH
- Sponsors AstraZeneca; AstraZeneca AB
Most Recent Events
- 10 Feb 2026 Study primary endpoint has been changed.
- 10 Feb 2026 Planned End Date changed from 28 May 2025 to 31 Dec 2026.
- 01 Oct 2025 According to a HUTCHMED media release, results from this trial will be presented at the European Society for Medical Oncology (ESMO) Congress 2025, taking place on October 17-21, 2025 in Berlin, Germany.