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An Open-Label, Multicenter, First-in-Human, Dose-Escalation, Phase 1 / 2 Study of INBRX-105 and INBRX-105 in Combination With Pembrolizumab in Patients With Locally Advanced or Metastatic Solid Tumors

Trial Profile

An Open-Label, Multicenter, First-in-Human, Dose-Escalation, Phase 1 / 2 Study of INBRX-105 and INBRX-105 in Combination With Pembrolizumab in Patients With Locally Advanced or Metastatic Solid Tumors

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 25 Oct 2024

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At a glance

  • Drugs INBRX 105 (Primary) ; Pembrolizumab (Primary)
  • Indications Adenocarcinoma; Carcinoma; Gastric cancer; Head and neck cancer; Hodgkin's disease; Malignant melanoma; Nasopharyngeal cancer; Non-Hodgkin's lymphoma; Non-small cell lung cancer; Oesophageal cancer; Oropharyngeal cancer; Renal cell carcinoma; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; First in man
  • Acronyms PDL1x41BB
  • Sponsors Inhibrx

Most Recent Events

  • 23 Oct 2024 Status changed from active, no longer recruiting to discontinued.
  • 25 Jul 2024 Status changed from recruiting to active, no longer recruiting.
  • 06 Mar 2023 According to an Inhibrx media release, company expects to announce clinical data from these cohorts during the second half of 2023.

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