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A Double-blind, Randomised, Placebo-controlled, Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple-ascending Doses of Intravenously Administered STT-5058 in Otherwise Healthy Subjects With Elevated Triglyceride Levels and Single-ascending and Multiple Doses of Subcutaneously Administered STT-5058 in Otherwise Healthy Subjects With Elevated Triglyceride Levels and Patient Volunteers With Hypertriglyceridemia

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Trial Profile

A Double-blind, Randomised, Placebo-controlled, Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple-ascending Doses of Intravenously Administered STT-5058 in Otherwise Healthy Subjects With Elevated Triglyceride Levels and Single-ascending and Multiple Doses of Subcutaneously Administered STT-5058 in Otherwise Healthy Subjects With Elevated Triglyceride Levels and Patient Volunteers With Hypertriglyceridemia

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 24 Jan 2023

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At a glance

  • Drugs ARGX 116 (Primary) ; ARGX 116 (Primary)
  • Indications Dyslipidaemias; Hypertriglyceridaemia
  • Focus Adverse reactions; First in man
  • Sponsors Staten Biotechnology

    • Most Recent Events

    • 19 Jan 2023 Status changed from active, no longer recruiting to discontinued.
    • 05 Oct 2022 Planned End Date changed from 1 Oct 2022 to 1 Nov 2022.
    • 05 Oct 2022 Planned primary completion date changed from 1 Oct 2022 to 1 Nov 2022.

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