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Intermittent or continuous Panitumumab plus FOLFIRI for first-line treatment of patients with RAS/B-RAF wild-type metastatic colorectal cancer: a randomized phase 2 trial

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Trial Profile

Intermittent or continuous Panitumumab plus FOLFIRI for first-line treatment of patients with RAS/B-RAF wild-type metastatic colorectal cancer: a randomized phase 2 trial

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 12 Jun 2024

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At a glance

  • Drugs Panitumumab (Primary) ; Fluorouracil; Folinic acid; Irinotecan
  • Indications Colorectal cancer
  • Focus Therapeutic Use
  • Acronyms IMPROVE

Most Recent Events

  • 06 Jun 2023 Result of an update of survival/toxicity and preliminary results of genomic alterations from IMPROVE study presented at the 59th Annual Meeting of the American Society of Clinical Oncology
  • 07 Jun 2022 Primary endpoint has been met. (Progression-free survival on treatment (PFSOT) at 12months), as per Results presented at the 58th Annual Meeting of the American Society of Clinical Oncology
  • 07 Jun 2022 Results presented at the 58th Annual Meeting of the American Society of Clinical Oncology

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