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Neoadjuvant Letrozole and Palbociclib in patients with Stage II-IIIb breast cancer, HR (+) / HER2 (-) phenotype and Intermediate (18-25) or High (>25) Recurrence-Score by Oncotype-DX; analysis of RS and pathological changes at surgery

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Trial Profile

Neoadjuvant Letrozole and Palbociclib in patients with Stage II-IIIb breast cancer, HR (+) / HER2 (-) phenotype and Intermediate (18-25) or High (>25) Recurrence-Score by Oncotype-DX; analysis of RS and pathological changes at surgery

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 25 Jul 2022

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At a glance

  • Drugs Letrozole (Primary) ; Palbociclib (Primary)
  • Indications Adenocarcinoma; Advanced breast cancer; Early breast cancer; HER2 negative breast cancer
  • Focus Therapeutic Use
  • Acronyms DxCARTES
  • Most Recent Events

    • 06 Feb 2020 Status changed from recruiting to completed.
    • 22 Aug 2019 Status changed from not yet recruiting to recruiting.
    • 06 Mar 2019 Planned primary completion date changed from 31 Jan 2019 to 31 May 2019.

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