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A Randomized, Open-Label, Two-Treatment, Two-Period, Two-Way Crossover Study to Investigate the Relative Bioavailability of Entrectinib Capsule Formulations F1 and F06 Under Fed Conditions in Healthy Subjects

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Trial Profile

A Randomized, Open-Label, Two-Treatment, Two-Period, Two-Way Crossover Study to Investigate the Relative Bioavailability of Entrectinib Capsule Formulations F1 and F06 Under Fed Conditions in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 27 Jan 2021

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At a glance

  • Drugs Entrectinib (Primary)
  • Indications Acute myelomonocytic leukaemia; Brain metastases; Malignant melanoma; Non-small cell lung cancer; Solid tumours; Uveal melanoma
  • Focus Pharmacokinetics
  • Sponsors Genentech

    • Most Recent Events

    • 18 Jan 2021 Results from NCT02097810 ,NCT03796260 and NCT03796013 in patients and healthy subjects assessing pharmacokinetics and disposition of entrectinib,pharmacokinetics and disposition of entrectinib,published in the Investigational New Drugs
    • 25 Feb 2020 Status changed from recruiting to completed.
    • 11 Jan 2019 New trial record

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