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Phase I, Interventional, Single Arm, Open Label, Treatment Study to Evaluate The Safety and Tolerability of CLL1-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies.

Trial Profile

Phase I, Interventional, Single Arm, Open Label, Treatment Study to Evaluate The Safety and Tolerability of CLL1-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies.

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 05 May 2023

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At a glance

  • Drugs CLL 1 CD33 cCAR (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Acute myeloid leukaemia; Haematological malignancies; Myelodysplastic syndromes; Myeloproliferative disorders
  • Focus Adverse reactions; First in man
  • Sponsors iCell Gene Therapeutics

Most Recent Events

  • 17 May 2021 Planned End Date changed from 30 Sep 2020 to 30 Sep 2022.
  • 17 May 2021 Planned primary completion date changed from 30 Sep 2020 to 30 Sep 2022.
  • 21 Jun 2020 Results (n=9) presented at the 25th Congress of the European Haematology Association.

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