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A Phase 1, Open-label, Multicenter Study of SYNB1891 Administered by Intratumoral Injection to Patients With Advanced/Metastatic Solid Tumors and Lymphoma Alone and in Combination With Atezolizumab

Trial Profile

A Phase 1, Open-label, Multicenter Study of SYNB1891 Administered by Intratumoral Injection to Patients With Advanced/Metastatic Solid Tumors and Lymphoma Alone and in Combination With Atezolizumab

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 08 May 2024

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At a glance

  • Drugs Atezolizumab (Primary) ; SYNB 1891 (Primary)
  • Indications Lymphoma; Malignant melanoma; Small cell lung cancer; Solid tumours; Vulval disorders
  • Focus Adverse reactions; First in man
  • Sponsors Synlogic

Most Recent Events

  • 10 Nov 2021 Status changed from recruiting to active, no longer recruiting according to a Synlogic media release.
  • 12 Aug 2021 According to a Synlogic media release, data from the combination arm is expected by the end of the year.
  • 10 Apr 2021 Interim analysis (n=11) presented at the 112th Annual Meeting of the American Association for Cancer Research

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