Phase 2 Study (With Safety Lead in) of the Safety, Tolerability and Efficacy of Anti-CTLA4 (Ipilimumab) and Anti-PD-1 (Nivolumab) in Combination With Radiation Therapy to 50-66 Gy in Low-Intermediate Volume, Local-Regionally Advanced HPV-Positive Oropharyngeal Squamous Cell Carcinoma (OPSCC)
Latest Information Update: 27 Jun 2025
At a glance
- Drugs Ipilimumab (Primary) ; Nivolumab (Primary) ; Ropidoxuridine
- Indications Oropharyngeal cancer; Squamous cell cancer
- Focus Adverse reactions; Therapeutic Use
Most Recent Events
- 24 Jun 2025 Planned End Date changed from 30 Jun 2025 to 30 Jun 2026.
- 24 Jun 2025 Planned primary completion date changed from 30 Jun 2025 to 30 Jun 2026.
- 22 Oct 2024 Planned number of patients changed from 180 to 37.