Trial Profile

A Phase 2 Randomized Study of Adjuvant Immunotherapy With the Personalized Cancer Vaccine mRNA-4157 and Pembrolizumab Versus Pembrolizumab Alone After Complete Resection of High-Risk Melanoma (KEYNOTE- 942)

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 11 Jun 2025

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At a glance

30 Apr 2025 Results of the dynamics of T cell and T cell receptor (TCR) repertoire in peripheral blood following mRNA-4157 plus pembro or pembro alone presented at the 116th Annual Meeting of the American Association for Cancer Research
06 Jun 2024 Planned number of patients changed from 257 to 267.
04 Jun 2024 Results after 3-year follow up presented at the 60th Annual Meeting of the American Society of Clinical Oncology.

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