Trial Profile

QUILT-3.063: A Phase 2 Study of Combination Therapy With an IL-15 Superagonist (N-803), Off-the-shelf CD16-targeted Natural Killer Cells (haNK), and Avelumab Without Cytotoxic Chemotherapy in Subjects With Merkel Cell Carcinoma (MCC) That Has Progressed on or After Treatment With a Checkpoint Inhibitor

Status: Discontinued

Phase of Trial: Phase II

Latest Information Update: 13 Aug 2024

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At a glance

Drugs Avelumab (Primary) ; High affinity CD-expressing natural killer cell therapy ImmunityBio (Primary) ; Nogapendekin alfa inbakicept (Primary)
Indications Merkel cell carcinoma
Focus Adverse reactions; Therapeutic Use
Sponsors ImmunityBio; NantKwest

01 Oct 2021 Status changed from recruiting to discontinued as not meeting recruitment goal.
16 Mar 2021 Status changed to recruiting.
19 Mar 2020 According to a NantKwest media release, first patient has been dosed.

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