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Phase I Study of Dual Immune Checkpoint Blockade (Anti-PD-L1 (Durvalumab) (MEDI4736) and Anti-CTLA4 (Tremelimumab) Plus Yttrium-90 (Y-90) Radioembolization & Stereotactic Body Radiation Therapy (SBRT) in Refractory Metastatic MSS (Microsatellite Stable) Colorectal Cancer With Liver Metastases

Trial Profile

Phase I Study of Dual Immune Checkpoint Blockade (Anti-PD-L1 (Durvalumab) (MEDI4736) and Anti-CTLA4 (Tremelimumab) Plus Yttrium-90 (Y-90) Radioembolization & Stereotactic Body Radiation Therapy (SBRT) in Refractory Metastatic MSS (Microsatellite Stable) Colorectal Cancer With Liver Metastases

Status: Withdrawn prior to enrolment
Phase of Trial: Phase I

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs Durvalumab (Primary) ; Tremelimumab (Primary) ; Yttrium-90 (Primary)
  • Indications Colorectal cancer; Liver metastases
  • Focus Adverse reactions

Most Recent Events

  • 20 Jun 2019 Planned initiation date changed from 1 May 2019 to 1 Aug 2019.
  • 26 Apr 2019 Planned initiation date changed from 1 Mar 2019 to 1 May 2019.
  • 21 Jan 2019 New trial record

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