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Phase IIa Randomized, Double Blind, Placebo Controlled, Multiple Dose Study on ABX464 in Combination With Methotrexate (MTX), in Patients With Moderate to Severe Active Rheumatoid Arthritis Who Have Inadequate Response to MTX or/and to Anti-Tnfα, or Intolerance to Anti-Tnfα

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Trial Profile

Phase IIa Randomized, Double Blind, Placebo Controlled, Multiple Dose Study on ABX464 in Combination With Methotrexate (MTX), in Patients With Moderate to Severe Active Rheumatoid Arthritis Who Have Inadequate Response to MTX or/and to Anti-Tnfα, or Intolerance to Anti-Tnfα

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 17 Feb 2023

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At a glance

  • Drugs Obefazimod (Primary) ; Methotrexate
  • Indications Rheumatoid arthritis
  • Focus Adverse reactions; Proof of concept
  • Sponsors Abivax

    • Most Recent Events

    • 04 Jun 2022 40 patients enrolled in the ongoing open label maintenance study with ABX464 50 mg qd as per results presented at the 23rd Annual Congress of the European League Against Rheumatism
    • 04 Jun 2022 Results presented at the 23rd Annual Congress of the European League Against Rheumatism
    • 31 May 2022 Results published in the Annals of the Rheumatic Diseases

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