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Phase II Trial Evaluating the Efficacy and Safety of Neoadjuvant Neratinib and Chemotherapy in Early Stage Triple-Negative Breast Cancer Patients Who Exhibit Enhanced HER2 Signaling by Live Cell HER2 Signaling Transduction Analysis (FACT-2)

Trial Profile

Phase II Trial Evaluating the Efficacy and Safety of Neoadjuvant Neratinib and Chemotherapy in Early Stage Triple-Negative Breast Cancer Patients Who Exhibit Enhanced HER2 Signaling by Live Cell HER2 Signaling Transduction Analysis (FACT-2)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Dec 2023

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At a glance

  • Drugs Neratinib (Primary) ; Carboplatin; Paclitaxel
  • Indications Adenocarcinoma; Early breast cancer; Triple negative breast cancer
  • Focus Therapeutic Use
  • Acronyms FACT-2

Most Recent Events

  • 15 Dec 2023 Planned End Date changed from 15 Apr 2023 to 15 Dec 2024.
  • 15 Dec 2023 Planned primary completion date changed from 15 Oct 2020 to 15 Dec 2024.
  • 15 Dec 2023 Status changed from recruiting to active, no longer recruiting.

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