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A Phase 2, Open-Label, Randomized Study to Assess the Efficacy and Safety of Zolbetuximab (IMAB362) in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive, Metastatic Pancreatic Adenocarcinoma

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A Phase 2, Open-Label, Randomized Study to Assess the Efficacy and Safety of Zolbetuximab (IMAB362) in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive, Metastatic Pancreatic Adenocarcinoma

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 24 Oct 2024

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At a glance

  • Drugs Gemcitabine (Primary) ; Paclitaxel (Primary) ; Zolbetuximab (Primary)
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Astellas Pharma Global Development

    • Most Recent Events

    • 19 Sep 2024 Planned End Date changed from 30 Apr 2025 to 31 Aug 2026.
    • 19 Sep 2024 Planned primary completion date changed from 30 Sep 2024 to 31 Aug 2026.
    • 17 Sep 2024 Trial design presented at the 49th European Society for Medical Oncology Congress

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