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Open-label, single administration, ascending dose study to explore the safety and efficacy of a gene therapy with a unilateral subretinal administration of HORA RLBP1 in patients with a retinal dystrophy harbouring biallelic mutations in the RLBP1 gene leading to a defect in CRALBP expression

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Trial Profile

Open-label, single administration, ascending dose study to explore the safety and efficacy of a gene therapy with a unilateral subretinal administration of HORA RLBP1 in patients with a retinal dystrophy harbouring biallelic mutations in the RLBP1 gene leading to a defect in CRALBP expression

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 25 Mar 2022

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At a glance

  • Drugs HORA-RLBP1 (Primary)
  • Indications Retinal dystrophies
  • Focus Adverse reactions; First in man
  • Sponsors Coave Therapeutics

Most Recent Events

  • 28 Feb 2019 Status changed from not yet recruiting to recruiting.
  • 05 Feb 2019 New trial record

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