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A Phase 1, Open-Label, Fixed-Sequence, Drug-Drug Interaction Study to Evaluate the Effects of Tucatinib of the Pharmacokinetics of Metformin in Healthy Male and Female Subjects

Trial Profile

A Phase 1, Open-Label, Fixed-Sequence, Drug-Drug Interaction Study to Evaluate the Effects of Tucatinib of the Pharmacokinetics of Metformin in Healthy Male and Female Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 29 Oct 2020

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At a glance

  • Drugs Tucatinib (Primary) ; Iohexol; Metformin
  • Indications Breast cancer; Cholangiocarcinoma; Colorectal cancer; Gallbladder cancer; Gastrointestinal cancer; Non-small cell lung cancer
  • Focus Pharmacokinetics
  • Sponsors Seagen; Seattle Genetics

Most Recent Events

  • 24 Jun 2020 Results presented at the 111th Annual Meeting of the American Association for Cancer Research - II
  • 25 Mar 2019 Status changed from recruiting to completed.
  • 28 Feb 2019 Status changed from not yet recruiting to recruiting.

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