A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate Pembrolizumab Versus Placebo as Adjuvant Therapy Following Surgery and Radiation in Participants With High-risk Locally Advanced Cutaneous Squamous Cell Carcinoma (LA cSCC) (KEYNOTE-630)
Latest Information Update: 24 Jun 2025
At a glance
- Drugs Pembrolizumab (Primary)
- Indications Carcinoma; Skin cancer; Squamous cell cancer
- Focus Registrational; Therapeutic Use
- Acronyms KEYNOTE-630
- Sponsors Merck Sharp & Dohme; Merck Sharp & Dohme Corp.
Most Recent Events
- 17 Jun 2025 Timeframe for primary endpoint changed from 60 months to 62 months.
- 28 Nov 2024 Planned End Date changed from 29 Sep 2028 to 22 Dec 2025.
- 15 Apr 2024 Status changed from recruiting to active, no longer recruiting.