Trial Profile

Cryotherapy Under Interventional Radiology Combined With in Situ Ipilimumab and a Flat Dose of Nivolumab in Stage IIIB/C Melanoma. Prospective Proof of Concept Study.

Status: Completed

Phase of Trial: Phase I/II

Latest Information Update: 29 May 2024

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At a glance

Drugs Ipilimumab (Primary) ; Nivolumab (Primary)
Indications Malignant melanoma
Focus Proof of concept; Therapeutic Use
Acronyms CRIRIN

Most Recent Events

01 May 2024 Results (n=15), demonstrating the feasibility and safety of neoadjuvant and in situ immunotherapy with cryoablation of metastatic lymph nodes in patients with stage IIIB/IIIC melanomas, presented in the Cardiovascular and Interventional Radiology.
29 Apr 2022 Status changed from active, no longer recruiting to completed.
20 Jan 2022 Planned End Date changed from 1 Oct 2022 to 1 Mar 2022.

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