Trial Profile

A Parallel Arm Phase 1b/2a Study of DKN-01 as Monotherapy or in Combination With Docetaxel for the Treatment of Advanced Prostate Cancer With Elevated DKK1

Status: Discontinued

Phase of Trial: Phase I/II

Latest Information Update: 15 Jun 2025

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At a glance

Drugs Docetaxel (Primary) ; Sirexatamab (Primary)
Indications Adenocarcinoma; Carcinoma; Prostate cancer
Focus Adverse reactions; Therapeutic Use

Most Recent Events

01 Jun 2025 Results assessing DKN-01 as monotherapy or in combination with docetaxel for the treatment of metastatic castration-resistant prostate cancer were published in the Prostate Cancer and Prostatic Diseases.
30 Jan 2023 Status changed from active, no longer recruiting to discontinued.
11 Jul 2022 Planned End Date changed from 1 Dec 2022 to 31 Aug 2023.

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