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A 24-week Phase 2, Double-blind, Randomized, Placebo- Controlled, Single-center Safety and Efficacy Study to Evaluate Overall Safety and Tolerability of Co-administration of Tesofensine and Metoprolol in Subjects With Hypothalamic Injury-induced Obesity (HIO), and With a 24-week Open-label Extension, in Total 48 Weeks

Trial Profile

A 24-week Phase 2, Double-blind, Randomized, Placebo- Controlled, Single-center Safety and Efficacy Study to Evaluate Overall Safety and Tolerability of Co-administration of Tesofensine and Metoprolol in Subjects With Hypothalamic Injury-induced Obesity (HIO), and With a 24-week Open-label Extension, in Total 48 Weeks

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 16 Feb 2024

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At a glance

  • Drugs Metoprolol/tesofensine (Primary)
  • Indications Obesity
  • Focus Adverse reactions
  • Sponsors Saniona
  • Most Recent Events

    • 09 May 2022 Results investigating the safety and efficacy of Tesomet (0.5 mg tesofensine/50 mg metoprolol) in adults with hypothalamic obesity, published in the European Journal of Endocrinology
    • 23 Mar 2021 Results assessing safety and efficacy of Tesomet (co-administration of 0.5mg tesofensine and 50mg metoprolol) in hypopituitary patients with acquired hypothalamic obesity, presented at the 103rd Annual Meeting of the Endocrine Society
    • 15 Mar 2021 According to a Saniona media release, data will be presented at the Endocrine Society 2021 Annual Meeting (ENDO 2021).

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