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A Phase 1/2 clinical trial of OCU400 (AAV-NR2E3), a modifier gene therapy candidate for the treatment of retinitis pigmentosa resulting from genetic mutations found in NR2E3 and RHO

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Trial Profile

A Phase 1/2 clinical trial of OCU400 (AAV-NR2E3), a modifier gene therapy candidate for the treatment of retinitis pigmentosa resulting from genetic mutations found in NR2E3 and RHO

Status: Planning
Phase of Trial: Phase I/II

Latest Information Update: 12 Jan 2022

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At a glance

  • Drugs OCU 400 (Primary)
  • Indications Retinal degeneration; Retinal disorders; Retinitis pigmentosa
  • Focus Adverse reactions; First in man; Proof of concept; Therapeutic Use
  • Sponsors Ocugen

    • Most Recent Events

    • 06 Jan 2022 According to an Ocugen media release, this trial is expected to initiate in Q1 2022.
    • 09 Dec 2021 According to an Ocugen media release, U.S. Food and Drug Administration (FDA) has accepted the Investigational New Drug application (IND) to initiate this study.
    • 09 Nov 2021 According to an Ocugen media release, the company is planning to initiate this clinical trial in the United States around the end of 2021.

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