A Phase 1/2 Open Label, Multicenter, Dose Escalation and Expansion Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HM43239 in Patients with Relapsed or Refractory Acute Myeloid Leukemia (AML)
Latest Information Update: 20 Feb 2026
At a glance
- Drugs Tuspetinib (Primary) ; Azacitidine; Venetoclax
- Indications Acute myeloid leukaemia
- Focus Adverse reactions; First in man; Pharmacokinetics
- Acronyms APTIVATE; TUSCANY; TUSCANY Triplet Trial
- Sponsors Aptose Biosciences; Hanmi Pharmaceutical
Most Recent Events
- 06 Dec 2025 According to an Aptose Biosciences media release, data from this study featured at the 67th American Society of Hematology (ASH) Annual Meeting in Orlando, FL.
- 06 Dec 2025 Results published in the Media Release
- 03 Nov 2025 Results presented in the Aptose Biosciences Media Release.