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Non-randomized, three-period, fixed-sequence, multiple-dose trial, open label study of drug- drug interaction between doravirine, elbasvir and grazoprevir

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Trial Profile

Non-randomized, three-period, fixed-sequence, multiple-dose trial, open label study of drug- drug interaction between doravirine, elbasvir and grazoprevir

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 27 Feb 2019

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At a glance

  • Drugs Doravirine (Primary) ; Elbasvir (Primary) ; Grazoprevir (Primary)
  • Indications Hepatitis C; HIV-1 infections
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use

    • Most Recent Events

    • 27 Feb 2019 New trial record
    • 19 Feb 2019 Results assessing drug-drug interactions (DDIs) between doravirine and two HCV treatments in two phase 1 drug interaction trials (MK-1439-053, MK-1439-050) published in the Antimicrobial Agents and Chemotherapy.

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