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Basket Combination Study of Inhibitors of DNA Damage Response, Angiogenesis and Programmed Death Ligand 1 in Patients With Advanced Solid Tumors

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Trial Profile

Basket Combination Study of Inhibitors of DNA Damage Response, Angiogenesis and Programmed Death Ligand 1 in Patients With Advanced Solid Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 04 Apr 2025

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At a glance

  • Drugs Cediranib (Primary) ; Durvalumab (Primary) ; Olaparib (Primary)
  • Indications Adenocarcinoma; Colorectal cancer; Leiomyosarcoma; Pancreatic cancer; Solid tumours
  • Focus Adverse reactions; Biomarker; Pharmacodynamics; Pharmacogenomic
  • Acronyms DAPPER

Most Recent Events

  • 30 Mar 2025 Planned End Date changed from 1 Jan 2025 to 1 Jan 2026.
  • 30 Mar 2025 Planned primary completion date changed from 1 Jan 2025 to 1 Jan 2026.
  • 12 Mar 2024 Planned End Date changed from 1 Dec 2023 to 1 Jan 2025.

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